DNA & Complete Genetic Dominance

Traits of Simple Inheritance: Melanin (Eye Color) & Myopia

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Recessive Phenotype: Lack of Melanin in Iris - vicki s. first science
Recessive Phenotype: Lack of Melanin in Iris - vicki s. first science
Learn about genetic traits by examining some of your own! This article explores the genetic of iris pigment and nearsightedness.

Before discussing eye pigment and myopia, it is first necessary to review some of the genetic terminology related to these aspects of heredity.

Alleles: Variations of a Gene

Alleles are variations of a gene. A diploid organism gets one set of alleles (genes) from one parent and the other set of alleles from the other parent.

Some of the traits that we have are based on simple inheritance where one version of a gene (dominant allele) masks the expression of the other version of that gene (recessive allele).

In writing, we represented dominant and recessive alleles with letters that distinguish the different types of alleles. A capital letter is used to represent the dominant allele and a lower-case letter is used to represent the recessive allele (example: dominant allele = P; recessive allele = p)

Homozygous or Heterozygous Genotype

When an organism has a pair of identical alleles for a character, they are said to be homozygous for that characteristic (PP, pp) When an organism has two different alleles for a gene (Pp) they are said to be heterozygous for that characteristic.

Dominant or Recessive Phenotypes

In cases if simple inheritance, where a characteristic is controlled by one pair of alleles and one allele is dominant over the other, this is called complete dominance. For that characteristic, an organism will have one of two phenotypes.

When an organism has the recessive phenotype, this means that both recessive alleles must be present (bb). With recessive traits, you know what the genotype is if the phenotype is recessive.

An organism showing the dominant phenotype can be homozygous or heterozygous for dominant allele (PP, Pp). It is more difficult to know genotype when dominant allele is involved.

Examples of Simple Inheritance of Traits that Show Complete Dominance

The characteristics listed below are products of simple inheritance. One can either possess the dominant phenotype or the recessive phenotype.

All of the following are dominant traits, meaning that if the trait described is present (non-blue eyes, nearsightedness) it is the dominant phenotype and the corresponding genotype would be either homozygous dominant or heterozygous. If the trait is absent (blue eyes, not nearsighted) the corresponding genotype is recessive.

Eye Color

We’re kind of cheating here. Eye color, as well as hair and skin color, is a complex trait. Not a case of simple inheritance. The main pigment is melanin, and the more melanin, the darker the color.

Although the genetics of eye color is complex, alleles for the production of melanin dominate those for lack of melanin. So if we evaluate eye color as being blue (recessive) or non-blue (dominant) we can treat it as a characteristic of simple inheritance.

Alleles: E, e

Dominant phenotype: non-blue eyes

Dominant genotype: E –

Recessive genotype: ee

Early Onset Myopia (childhood)

Nearsightedness, or myopia, is a complex trait with at least 4 gene loci involved, however the heritability of myopia is very high and shows a dominant pattern.

Alleles: M, m

Dominant phenotype: nearsightedness

Dominant genotype: M –

Recessive genotype: mm

More Examples of Simple Inheritance of Traits the Show Complete Dominance

There are many interesting phenotypic traits that you can examine and see if you have the dominant or recessive phenotype. For more information on genetics, see the website Science Prof Online or see the Suite 101 articles Genotype, Phenotype & Heredity, Dominant Human Genetic Traits (Mid-digital Hair, Hand Clasping & Bent Finger) and Simple Genetic Inheritance (Facial Dimples, Chin Cleft & Free Earlobes).

Sources

Thorpe ed. (2007) Biology 120 Lab Manual. Grand Valley State University.

Doezema, B. (2006) Biology 101 Lab Manual. Grand Rapids Community College.

Tami Port, MS, Tami Port

Tami Port - Tami Port is a college professor of cell and microbiology and creator of ScienceProfOnline.com, a free science education website.

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Comments

Apr 13, 2010 3:21 PM
Guest :
I'm learning about all of this in my science class in school. I find it all very intriguing and I was wondering if anyone knows of a website where they have the complex genetic inheritance or anything like that.
May 11, 2010 7:05 AM
Guest :
Good basic information
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